To evaluate the effect of different soil amendments on the yield and nutrient uptake of Salsola plant in the dry bed of Urmia Lake, an experiment was set up as a randomized complete block design with eight treatments and three replications in the 2013-2014 time period. These treatments included mycorrhiza usage, sand in the seed bed, plastic in the  depth of 70 cm, plastic in the  depth of 70 cm + Mycorrhiza, application of animal manure to improve the soil pH, sand + Mycorrhiza, treatments, animal manure + mycorrhiza, and control without consuming any materials. The results of data variance analysis indicated the difference between treatments in terms of quantitative and qualitative studied traits. Comparison of means by Tukey method showed that the effects of all treatments on the grain yield, 1000 grain weight, harvest index, and absorption of micro nutrient and macro nutrient elements in the grain were significant. Mean comparison also showed that the highest grain yield belonged to animal manure and animal manure +Mycorrhiza fertilizer treatments, while the least one its belonged to plastic and sand treatments. Also, the nutrients absorbed in the animal manure and animal manure + mycorrhiza treatments were more than those in others. Overall, Salsula plant can be planted in a lake bed and livestock manure and mycorrhiza can be used to improve the yield.